heterogeneous nuclear ribonucleoprotein L; hnRNP L (HNRNPL HNRPL P/OKcl14)

Function

• heterogeneous nuclear ribonucleoprotein involved in processing of pre-mRNAs
• associated with most nascent transcripts including those of the landmark giant loops of amphibian lampbrush chromosomes
• several isoelectric forms of the L protein are probably the results of post-translational modifications
• interacts with HNRPLL

Structure

contains 3 RRM domain (RNA recognition motif)s

Compartment

nucleus, nucleoplasm

More general terms

• heterogeneous nuclear ribonucleoprotein (hnRNP)
• RNA-binding protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P14866.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3191
• OMIM: https://mirror.omim.org/entry/164021
• OMIM: https://mirror.omim.org/entry/603083