cleavage stimulation factor, subunit 2, 64 kD, tau variant (CSTF2T, KIAA0689)

Function

• role in AAUAAA-independent mRNA polyadenylation in germ cells
• binds pre-mRNAs
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• contains 1 RRM domain (RNA recognition motif)

Compartment

nucleus

More general terms

• RNA-binding protein
• protein subunit
• phosphoprotein
• nuclear protein

Component of

• cleavage stimulation factor

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23283
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23283
• OMIM: https://mirror.omim.org/entry/611968
• UniProt: http://www.uniprot.org/uniprot/Q9H0L4.html