post-GPI attachment to proteins factor 2 (FGF receptor-activating protein 1, PGAP2, FRAG1)

Function

• role in the lipid remodeling steps of GPI-anchor maturation
• required for stable expression of GPI-anchored proteins at the cell surface (putative)
• interacts with PGAP2IP (putative)

Structure

belongs to the PGAP2 family

Compartment

Golgi membrane, endoplasmic reticulum membrane

Alternative splicing

named isoforms=3

Expression

• ubiquitously expressed, with highest levels in testis & pancreas

More general terms

• membrane protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2731
• UniProt: http://www.uniprot.org/uniprot/Q9UHJ9.html