V-set & immunoglobulin domain-containing protein 1; cell surface A33 antigen; glycoprotein A34 (VSIG1, GPA34)

Structure

• highly N-glycosylated
• appears not to contain significant amounts of O-linked carbohydrates or sialic acid in its sugar moieties
• contains 1 Ig-like C2-type domain (immunoglobulin-like)
• contains 1 Ig-like V-type domain (immunoglobulin-like)

Compartment

membrane

Expression

• detected only in stomach mucosa & testis >> pancreas (at protein level)

Pathology

• detected in gastric cancers (31%), esophageal carcinomas (50%) & ovarian cancers (23%)

More general terms

• V-set & immunoglobulin domain-containing protein (VSIG)
• glycoprotein
• membrane protein

Additional terms

• cell surface A33 antigen (glycoprotein A33, GPA33)

Database

• UniProt: http://www.uniprot.org/uniprot/Q86XK7.html