cell surface A33 antigen (glycoprotein A33, GPA33)

Function

• role in cell-cell recognition & signaling

Structure

• N-glycosylated, contains approximately 8 kD of N-linked carbohydrate
• palmitoylated
• contains 1 Ig-like C2-type domain (immunoglobulin-like)
• contains 1 Ig-like V-type domain (immunoglobulin-like)

Compartment

membrane

Expression

• expressed in normal gastrointestinal epithelium

Pathology

• expressed in 95% of colon cancers (but also expressed in normal gastrointestinal epithelium)

More general terms

• glycoprotein
• membrane protein

Additional terms

• V-set & immunoglobulin domain-containing protein 1; cell surface A33 antigen; glycoprotein A34 (VSIG1, GPA34)

Database

• OMIM: https://mirror.omim.org/entry/602171
• UniProt: http://www.uniprot.org/uniprot/Q99795.html