protein tyrosine phosphatase-like protein PTPLAD1 (protein-tyrosine phosphatase-like A domain-containing protein 1, butyrate-induced protein 1, B-ind1, hB-ind1, PTPLAD1, BIND1)

Function

• role in Rac1-signaling pathways leading to the modulation of gene expression
• interacts with RAC1

Structure

• belongs to the PTPLA family
• contains 1 CS domain

Compartment

membrane (putative)

Expression

• highly expressed in testis, kidney, brain, liver & weakly in skeletal muscle, spleen & heart
• induced by AKAP12 & histone deacetylase inhibitors such as Na+ butyrate

More general terms

• phosphoprotein
• membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9P035.html