protein-tyrosine phosphatase-like member A; Cementum attachment protein (PTPLA)

Function

• probable anti-phosphatase
• may have role in development, differentiation, & maintenance of different tissue types
• may play role in myogenesis & cardiogenesis

Structure

• belongs to the PTPLA family
• shares some similarity with tyrosine phosphatase proteins but probably has no phosphatase activity

Compartment

membrane (putative)

Alternative splicing

named isoforms=2

Expression

• highly expressed in the myocardium, & to a lesser extent in skeletal & smooth muscular tissues including those from stomach, jejunum, & bladder
• expressed in fetal heart

More general terms

• glycoprotein
• membrane protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9200
• UniProt: http://www.uniprot.org/uniprot/B0YJ81.html