heparan-sulfate 6-O-sulfotransferase 3; HS6ST-3 (HS6ST3)

Function

• 6-O-sulfation enzyme
• catalyzes transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparansulfate

3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine <--> adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 6-sulfate

Structure

belongs to the sulfotransferase 6 family

Compartment

membrane

More general terms

• sulfotransferase
• membrane protein
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8IZP7.html