alpha-1,4-N-acetylglucosaminyltransferase (Alpha4GnT, A4GNT)
Jump to navigation
Jump to search
Function
- glycosylation
- necessary for the synthesis of mucin type 3
- catalyzes transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans
Structure
- belongs to the alpha 1,4-glycosyltransferase family
- conserved DXD motif is involved in enzyme activity
Compartment
Golgi membrane
Expression
detected in stomach & pancreas
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q9UNA3.html
- ↑ GGDB; Note: glycogene database http://riodb.ibase.aist.go.jp/rcmg/ggdb/
- ↑ Functional glycomics gateway - GTase alpha-1,4-N-acetylglucosaminyltransferase http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewglycoEnzyme.jsp?gbpId=gt_hum_532