leucine-rich repeat-containing protein 26 (cytokeratin-associated protein, LRRC26, CAPC)

Structure

• contains 6 LRR repeats (leucine-rich repeats)

Compartment

• membrane (putative), cytoplasm, cytoskeleton
• although predicted to be a single-pass type 1 membrane protein, localizes in cytoplasm when expressed at high levels

Expression

• expressed highly in normal prostate & salivary gland
• weak expression in colon, pancreas, & intestine
• not expressed in other tissues

Pathology

• expressed highly in many cancer cell lines & in breast cancer, pancreatic cancer & colon cancer

More general terms

• membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q2I0M4.html