SLIT & NTRK-like protein 2 (SLITRK2, CXorf2, KIAA1854, SLITL1, UNQ9197/PRO34756)
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Function
- suppresses neurite outgrowth
Structure
- belongs to the SLITRK family
- contains 14 LRR repeats (leucine-rich repeats)
Compartment
membrane
Alternative splicing
named isoforms=2
Expression
- expressed predominantly in cerebral cortex, but also at low levels in spinal cord & medulla
- expressed in some astrocytic brain tumors, including astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas & primitive neuroectodermal tumors