SLIT & NTRK-like protein 3 (SLITRK3, KIAA0848)

Function

• suppresses neurite outgrowth

Structure

• belongs to the SLITRK family
• contains 20 LRR (leucine-rich) repeats

Compartment

membrane

Expression

• expressed in occipital lobe of cerebral cortex

Pathology

• expressed at higher levels in some astrocytic brain tumors, including astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors

More general terms

• SLIT & NTRK-like protein (SLITRK)
• membrane protein
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/O94933.html