pituitary tumor-transforming gene 1 protein-interacting protein; pituitary tumor-transforming gene protein-binding factor; PTTG-binding factor; PBF (PTTG1IP, C21orf1, C21orf3)
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Function
- may facilitate PTTG1 nuclear translocation
- interacts with PTTG1
Structure
contains 1 PSI domain
Compartment
- membrane; single-pass type 1 membrane protein (putative)
- cytoplasm; nucleus
- found in the cytoplasm & the nucleus[3]
Expression
- ubiquitous
- induced by transcription factor RUNX2
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/P53801.html
- ↑ Atlas of Genetics & Cytogenetics in Oncology & Haematology http://atlasgeneticsoncology.org/genes/PTTG1IPID41944ch21q22.html
- ↑ 3.0 3.1 Chien W, Pei L. A novel binding factor facilitates nuclear translocation and transcriptional activation function of the pituitary tumor- transforming gene product. J Biol Chem. 2000 Jun 23;275(25):19422-7. PMID: https://www.ncbi.nlm.nih.gov/pubmed/10781616