translationally-controlled tumor protein; TCTP; p23; histamine-releasing factor; HRF; fortilin (TPT1)

Function

• role in Ca+2 binding & microtubule stabilization
• interacts with STEAP3

Structure

belongs to the TCTP family

Compartment

cytoplasm

Expression

• found in several healthy & tumoral cells including: erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, & lymphomas
• expressed in placenta & prostate
• cannot be detected in kidney & renal cell carcinoma (RCC)

More general terms

• membrane protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7178
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7178
• OMIM: https://mirror.omim.org/entry/600763
• UniProt: http://www.uniprot.org/uniprot/P13693.html