notch homolog 2 N-terminal-like protein (NOTCH2NL N2N)

Function

• may function in the notch signaling pathway & regulate neutrophil differentiation
• interacts with ELA2
• cleaved by ELA2

Structure

• belongs to the NOTCH family
• contains 6 EGF-like domains

Compartment

secreted, cytoplasm

Alternative splicing

named isoforms=3

Expression

• widely expressed
• higher levels in leukocytes & lymph nodes

More general terms

• notch (Drosophila) homolog protein
• glycoprotein
• secreted protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3886
• UniProt: http://www.uniprot.org/uniprot/Q7Z3S9.html