high affinity immunoglobulin gamma Fc receptor IB (Fc-gamma RIB, FcRIB, hFcgammaR1B, IgG Fc receptor IB) (FCGR1B IGFRB)

Function

• may bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A
• may function in the humoral immune response

Structure

• belongs to the immunoglobulin superfamily, FCGR1 family
• contains 2 Ig-like C2-type domain (immunoglobulin-like)

Compartment

cell membrane

Alternative splicing

named isoforms=3

Expression

up-regulated by IFNG

More general terms

• glycoprotein
• Fc gamma receptor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2210
• OMIM: https://mirror.omim.org/entry/601502
• UniProt: http://www.uniprot.org/uniprot/Q92637.html