olfactory receptor 11H7 (olfactory receptor OR14-32, OR11H7P, OR11H7)
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Function
odorant receptor, activated by isovaleric acid
Structure
belongs to the G-protein coupled receptor 1 family
Compartment
Polymorphism
- a stop codon in the gene coding for OR11H7P at position Gln-227 is responsible for functional diversity producing thus a pseudogene
- hypersensitivity towards isovaleric acid is seen predominantly in individuals who carry at least one copy of the intact allele
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q8NGC8.html
- ↑ Human olfactory receptor Data exploratorium (HORDE) http://bip.weizmann.ac.il/cgi-bin/HORDE/showgene.pl?key=symbol&value=OR11H7P