GPI ethanolamine phosphate transferase 2 (phosphatidylinositol-glycan biosynthesis class G protein, PIG-G, GPI7 homolog, hGPI7, PIGG, GPI7, UNQ1930/PRO4405)

Function

• glycolipid biosynthesis, glycosylphosphatidylinositol- anchor biosynthesis
• ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis
• transfers ethanolamine phosphate to the GPI second mannose
• forms a complex with PIGF which stabilizes PIGG
• competes with PIGO for the binding of PIGF

Structure

belongs to the PIGG/PIGN/PIGO family, PIGG subfamily

Compartment

endoplasmic reticulum membrane

Alternative splicing

named isoforms=5

More general terms

• glycoprotein
• phosphotransferase
• transmembrane 12e protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q5H8A4.html