phosphatidylinositol-glycan biosynthesis class F protein; PIG-F; GPI11 homolog (PIGF)

Function

• role in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI
• glycolipid biosynthesis; GPI-anchor biosynthesis
• forms a complex with PIGG & PIGO
• PIGF is required to stabilize PIGG & PIGO

Structure

• belongs to the PIGF family

Compartment

• endoplasmic reticulum membrane
• multi-pass membrane protein (putative)

Alternative splicing

named isoforms=2

More general terms

• phosphatidylinositol-glycan biosynthesis protein (PIG-protein)
• transmembrane 6 protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5281
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5281
• OMIM: https://mirror.omim.org/entry/600153
• UniProt: http://www.uniprot.org/uniprot/Q07326.html