uronyl 2-sulfotransferase (UST, DS2ST)
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Function
- sulfotransferase
- catalyzes the transfer of sulfate to the position 2 of uronyl residues
- activity toward iduronyl residues in dermatan sulfate, & weaker activity toward glucuronyl residues of chondroitin sulfate
- no activity toward desulfated N-resulfated heparin
Structure
belongs to the sulfotransferase 3 family
Compartment
Golgi membrane
Expression
widely expressed