dual oxidase maturation factor 2 (dual oxidase activator 2, DUOXA2)

Function

• required for maturation & transport of DUOX2 from endoplasmic reticulum to plasma membrane
• role in thyroid hormone synthesis (putative)

Structure

• belongs to the DUOXA family
• N-glycosylated

Compartment

endoplasmic reticulum membrane

Expression

• specifically expressed in thyroid
• also detected in salivary glands

More general terms

• transmembrane 5 protein
• glycoprotein
• chaperonin; chaperone

Database

• UniProt: http://www.uniprot.org/uniprot/Q1HG44.html