HERV-R 7q21.2 provirus ancestral Env polyprotein; ERV3 envelope protein; HERV-R envelope protein, [Contains: Surface protein (SU); Transmembrane protein (TM)] (ERV3, ERV3-1)

Introduction

Also see endogenous retroviral envelope polyprotein

Expression

• expressed in adrenal, sebaceous glands, placenta > bone marrow, brain, breast, colon, heart, kidney, liver, lung, ovary, PBL, prostate, skin, spleen, testis, thymus, thyroid, trachea
• expressed in primitive adrenal cortex & placenta > developing nervous tissues, tongue, heart, gut, kidney, vertebrae, liver

Genetics

• gene is polymorphic with at least 5 different alleles
• intergenic, the closest flanking genes are ZNF117 & FLJ25037

More general terms

• endogenous retroviral envelope polyprotein
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q14264.html