solute carrier family 21 member 2; solute carrier organic anion transporter family member 2A1; prostaglandin transporter; PGT (SLCO2A1, SLC21A2)

Function

• role in prostaglandin function:
  • release of newly synthesized prostaglandins from cells
  • transepithelial transport of prostaglandins
  • clearance of prostaglandins from circulation
• transports PGD2, as well as PGE1, PGE2 & PGF2A

Structure

• belongs to the organo anion transporter (TC 2.A.60) family
• contains 1 Kazal-like domain

Compartment

membrane

Expression

ubiquitous

More general terms

• transmembrane 12 protein
• glycoprotein
• solute carrier family 21 (SLC21, SLC21A)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6578
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6578
• OMIM: https://mirror.omim.org/entry/601460
• UniProt: http://www.uniprot.org/uniprot/Q92959.html