scavenger receptor class F member 1 (endothelial cells scavenger receptor, acetyl LDL receptor, SCARF1, SREC, KIAA0149)

Function

• mediates the binding & degradation of acetylated low density lipoprotein (Ac-LDL).
• mediates heterophilic interactions, suggesting a function as an adhesion protein
• heterophilic interaction with SCARF2 via extracellular domain, suppressed by Ac-LDL

Structure

contains 6 EGF-like domains

Compartment

membrane

Expression

endothelial cells

More general terms

• scavenger receptor
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8578
• OMIM: https://mirror.omim.org/entry/607873
• UniProt: http://www.uniprot.org/uniprot/Q14162.html