taste receptor type 2 member 42 (T2R42, T2R55, TAS2R42, TAS2R55)

Function

• receptor may play a role in the perception of bitterness
• gustducin-linked
• role in sensing chemical composition of gastrointestinal content
• activity of TAS2R42 may stimulate alpha gustducin, mediate PLC-beta-2 activation & lead to the gating of TRPM5

Structure

belongs to the G-protein coupled receptor T2R family

Compartment

membrane; Multi-pass membrane protein

More general terms

• taste receptor, type 2
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3531
• UniProt: http://www.uniprot.org/uniprot/Q7RTR8.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=259288