non-homologous end joining (NHEJ)

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Introduction

pathway that repairs double-strand breaks in DNA

break ends are directly ligated without a homologous template, in contrast to homologous recombination

More general terms

Additional terms

References

  1. Khanna KK & Jackson SP. A double-strand breaks: signaling, repair and the cancer connection. Nature Genetics 27:247-54, 2001 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11242102
  2. Wikipedia: Non-homologous end joining http://en.wikipedia.org/wiki/Non-homologous_end_joining