solute carrier family 22 member 3; organic cation transporter 3; extraneuronal monoamine transporter; EMT (SLC22A3, EMTH, OCT3)

Function

• mediates potential-dependent transport of a variety of organic cations
• may play a significant role in the disposition of cationic neurotoxins & neurotransmitters in the brain

Structure

• belongs to the major facilitator superfamily, organic cation transporter family

Compartment

membrane

Expression

• expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney & brain cortex
• no expression detected in spleen

More general terms

• solute carrier family 22 (SLC22, SLC22A)
• glycoprotein
• transmembrane 6 protein
• major facilitator superfamily (MFS)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6581
• OMIM: https://mirror.omim.org/entry/604842
• UniProt: http://www.uniprot.org/uniprot/O75751.html