Zn+2-alpha-2-glycoprotein; Zn-alpha-2-glycoprotein; Zn-alpha-2-GP (AZGP1, ZAG, ZNGP1)

Function

• stimulates lipid degradation in adipocytes
• may bind polyunsaturated fatty acids
• interacts with PIP

Structure

• belongs to the MHC class I family
• contains 1 Ig-like C1-type (immunoglobulin-like) domain

Compartment

secreted

Expression

• blood plasma, seminal plasma, urine, saliva, sweat, epithelial cells of various human glands, liver

Pathology

• causes extensive fat losses associated with some advanced cancers
• may be associated with reduction of body fat in smokers

More general terms

• secreted protein
• glycoprotein
• metalloprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P25311.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=563
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:563
• OMIM: https://mirror.omim.org/entry/194460