granulocyte colony-stimulating factor; colony-stimulating factor 3; G-CSF; pluripoietin (CSF3, C17orf33, GCSF)

Function

• cytokine
• induces granulocytes

Structure

• monomer
• belongs to the IL-6 superfamily

Compartment

secreted

Alternative splicing

named isoforms=2

Pharmacology

• available as filgrastim under the names Neupogen or Granulokine (Amgen/Roche) & Granocyte (Rhone-Poulenc)

More general terms

• colony-stimulating factor (CSF)
• glycoprotein

More specific terms

• efbemalenograstim alfa-vuxw (Ryzneuta)
• filgrastim [G-CSF] (Neupogen, Lenograstim, Granulokine)
• omidubicel-onlv (Omisirge)

Additional terms

• granulocyte colony-stimulating factor receptor; G-CSF-R; CD114 (CSF3R, GCSFR)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1440
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1440
• OMIM: https://mirror.omim.org/entry/138970
• UniProt: http://www.uniprot.org/uniprot/P09919.html