tetraspanin-7; Tspan-7; transmembrane 4 superfamily member 2; cell surface glycoprotein A15; T-cell acute lymphoblastic leukemia-associated antigen 1; TALLA-1; membrane component, X chromosome, surface marker 1; CD231 (TSPAN7, A15, DXS1692E, MXS1, TM4SF2)

Function

• may be involved in cell proliferation & cell motility

Structure

belongs to the tetraspanin (TM4SF) family

Compartment

membrane

Expression

• not solely expressed in T-cells
• expressed in acute myelocytic leukemia cells of some patients

Pathology

• defects in TSPAN7 are the cause of X-linked mental retardation 58 (MRX58)

More general terms

• tetraspanin (transmembrane-4-superprotein)
• glycoprotein
• CD antigen

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7102
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7102
• OMIM: https://mirror.omim.org/entry/300096
• OMIM: https://mirror.omim.org/entry/300210
• UniProt: http://www.uniprot.org/uniprot/P41732.html