neutrophil gelatinase-associated lipocalin; NGAL; p25; 25 kD alpha-2-microglobulin-related subunit of MMP-9; lipocalin-2; oncogene 24p3 (LCN2, HNL, NGAL)

Function

• transport of small lipophilic substances (putative)
• forms a covalently linked, disulfide-bridged heterodimer with the 92 kD type V collagenase (MMP-9)

Structure

belongs to the calycin superfamily, lipocalin family

Compartment

secreted

Expression

• expressed in bone marrow & in tissues that are prone to exposure to microorganism
• high expression in bone marrow, uterus, prostate, salivary gland, stomach, appendix, colon, trachea & lungs
• not found in small intestine or peripheral blood leukocytes

More general terms

• glycoprotein
• lipocalin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3934
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3934
• OMIM: https://mirror.omim.org/entry/600181
• UniProt: http://www.uniprot.org/uniprot/P80188.html