carboxypeptidase N subunit 2 (carboxypeptidase N polypeptide 2, carboxypeptidase N 83 kD chain, carboxypeptidase N regulatory subunit, carboxypeptidase N large subunit, CPN2, ACBP)

Function

• 83 kD subunit binds & stabilizes catalytic subunit & keeps it in circulation
• under some circumstances it may be an allosteric modifier of the catalytic subunit

Structure

• contains 13 LRR repeats (leucine-rich repeats)
• whether or not any Cys participate in intrachain bonds is unknown, but they do not form interchain disulfide bonds with the catalytic subunit

Compartment

secreted

More general terms

• protein subunit
• glycoprotein

Component of

• carboxypeptidase-N, plasma carboxypeptidase-B, kininase-1, anaphylatoxin inactivator or arginine carboxypeptidase

Database

• UniProt: http://www.uniprot.org/uniprot/P22792.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1370
• OMIM: https://mirror.omim.org/entry/603104
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1370