splicing factor arginine/serine-rich 10; transformer-2-beta; HTRA2-beta; transformer 2 protein homolog (SFRS10, TRA2B)

Function

• sequence-specific RNA-binding protei
• pre-mRNA splicing
• interacts with SAFB1, RNPS1, phosphorylated FUSIP1
• binds to A3 enhancer proteins SRp75, SRp55, SRp40, SRp30

Compartment

nuclear

Expression

• expressed in heart, skeletal muscle, pancreas > kidney, placenta, brain > kidney, liver

More general terms

• splicing factor arginine/serine-rich (SFRS)
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/602719
• UniProt: http://www.uniprot.org/uniprot/P62995.html