protein kinase C delta-binding protein (serum deprivation response factor-related gene product that binds to C-kinase, hSRBC) (PRKCDBP SRBC)
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Function
- seems to have an immune potentiation function
- interacts with PRKCD & with phosphatidylserine
- phosphatidylserine may form a bridge between PKC & PKC-binding partners & stabilize the binding (putative)
- in vitro, phosphorylated by PRKCD
Structure
belongs to the PTRF/SDPR family
Expression
- strongly expressed in mammary & epithelial cells
- down-regulated in breast & lung cancer cell lines