mitochondrial enolase superfamily member 1 (antisense RNA to thymidylate synthase, rTS, ENOSF1, RTS, TYMSAS)

Function

• may regulate thymidylate synthase activity
• could be sumoylated

Cofactor:

• divalent metal ions, Mg+2 seems to be the preferred ion

Structure

• belongs to the mandelate racemase/muconate lactonizing enzyme family ENOSF1 subfamily

Compartment

mitochondria (probable)

Alternative splicing

named isoforms=3

Notes

• originally identified as a gene coding for an antisense RNA to thymidylate synthase

More general terms

• mitochondrial protein
• phosphoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5555
• OMIM: https://mirror.omim.org/entry/607427
• UniProt: http://www.uniprot.org/uniprot/Q7L5Y1.html