trichilemmoma

Etiology

• Cowden syndrome

Pathology

• benign tumor derived from the outer root sheath epithelium of a hair follicle
• it consist of cells with pale-staining cytoplasm with abundant glycogen
• lobular downgrowth of cells with clear, expanded, faintly glassy cytoplasm

Clinical manifestations

• multiple asymptomatic facial papules (case report)
  • flesh-colored papules localized to the central face

* images

Diagnostic procedures

• shave biopsy

Management

• topical sirolumus, 0.2%, gel daily (maybe 1 year of treatment)
  • may be used in combination with erbium-yttrium aluminum garnet laser therapy

More general terms

• glandular epithelial neoplasm

Additional terms

• Cowden's disease; multiple hamartoma syndrome including Lhermitte-Duclos disease (cerebelloparenchymal disorder)