Capz-interacting protein (protein kinase substrate CapZIP, RCSD domain-containing protein 1, RCSD1, CAPZIP)

Function

• stress-induced phosphorylation of CAPZIP may regulate ability of F-actin-capping protein to remodel actin filament assembly
• interacts with CAPZA2 & CAPZB
• dephosphorylation results in its dissociation from CAPZA2

Structure

contains 1 RCSD domain

Alternative splicing

named isoforms=2

Expression

• expressed in skeletal muscle > cardiac muscle
• also expressed in several lymphoid organs, including spleen, thymus, peripheral blood leukocytes, lymph node & bone marrow

More general terms

• phosphoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9224
• UniProt: http://www.uniprot.org/uniprot/Q6JBY9.html