F actin-capping protein, cCAP39, MCP or Cap-Z protein
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Function
- F-actin-capping proteins bind to the fast growing ends of actin filaments (barbed end) thus blocking the exchange of subunits at these ends (Ca+2-independent)
- unlike other capping proteins (such as gelsolin & severin), these proteins do not sever actin filaments
Subunits
- F-actin capping protein alpha subunit
- F-actin capping protein beta subunit
More general terms
Additional terms
- F-actin capping protein alpha-1 subunit (CapZ alpha-1, CAPZA1)
- F-actin-capping protein subunit alpha-2 (CapZ alpha-2, CAPZA2)
- F-actin-capping protein subunit beta (CapZ beta, CAPZB)
References
- ↑ Yu FX, Johnston PA, Sudhof TC, Yin HL. gCap39, a calcium ion- and polyphosphoinositide-regulated actin capping protein. Science. 1990 Dec 7;250(4986):1413-5. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2255912
- ↑ Stossel TP. On the crawling of animal cells. Science. 1993 May 21;260(5111):1086-94. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8493552
- ↑ Molecular Cell Biology (2nd ed) Darnell J; Lodish H & Baltimore D (eds), Scientific American Books, WH Freeman, NY 1990, pg 896