protein CARP; dermal papilla-derived protein 5 (CARP, FAM188A, C10orf97, DERP5, MSTP126, My042)

Function

• may have pro-apoptotic function
• overexpression significantly inhibits cell proliferation in several tumor cell lines

Structure

belongs to the CARP family

Compartment

nucleus

Alternative splicing

named isoforms=2

Expression

• highly expressed in heart, skeletal muscle, & kidney
• weak expression in liver & brain

Notes

• named CARP for 'CARD domain-containing protein'
• however, no CARD domain is detected by any prediction tool

More general terms

• nuclear protein
• phosphoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8001
• UniProt: http://www.uniprot.org/uniprot/Q9H8M7.html