Target of EGR1 protein 1 (TOE1)

Function

• inhibits cell growth rate & cell cycle
• induces CDKN1A expression as well as TGF-beta expression
• mediates inhibitory growth effect of EGR1

Structure

• belongs to the CAF1 family
• contains 1 C3H1-type zinc finger

Compartment

• nucleus, nucleolus, nuclear speckle
• localizes to nuclear speckles

More general terms

• zinc finger protein
• nuclear protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q96GM8.html