tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6; tRNA(m1A58)-methyltransferase subunit TRM6; tRNA(m1A58)MTase subunit TRM6 (TRM6, TRMT6, KIAA1153)

Function

• substrate-binding subunit of tRNA adenine-N1-methyltransferase
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

belongs to the TRM6/GCD10 family

Compartment

nucleus

Alternative splicing

named isoforms=2

Expression

expressed in brain, liver, testis & ovary

More general terms

• protein subunit
• phosphoprotein
• nuclear protein

Component of

• tRNA (adenine-N(1)-)-methyltransferase

Database

• UniProt: http://www.uniprot.org/uniprot/Q9UJA5.html