leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2, LRRFIP2)

Function

• may function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin
• interacts with DVL3 & FLII

Structure

belongs to the LRRFIP family

Alternative splicing

named isoforms=3

Expression

• ubiquitous
• higher expression in heart & skeletal muscle

More general terms

• phosphoprotein
• leucine-rich repeat-containing protein (LRRC)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9Y608.html