formin-binding protein 4 (formin-binding protein 30, FNBP4, FBP30, KIAA1014)

Function

• binds Arg/Gly-rich-flanked Pro-rich domain of KHDRBS1/SAM68
• Arg methylation in these regions has no effect on binding
• WW domains interact with Arg/Gly-rich-flanked Pro-rich domains found in several WW domain-binding proteins
• N-terminal WW domain has the greater ligand-binding ability
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

contains 2 WW domains

More general terms

• phosphoprotein
• formin binding protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8N3X1.html