pleckstrin homology-like domain family B member 2 (protein LL5-beta, PHLDB2, LL5B)

Function

• role in assembly of postsynaptic apparatus (putative)
• role in acetylcholine receptor aggregation in postsynaptic membrane
• interacts with FLNC

Structure

• contains 1 PH domain the mediates binding to phosphoinositides

Compartment

• cytoplasm, peripheral membrane
• translocates to plasma membrane at high levels of PIP3
• at low levels of PIP3 is translocated to vesicles

Alternative splicing

named isoforms=3

More general terms

• pleckstrin homology-like domain family B
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q86SQ0.html