nucleoporin NUP53 (nuclear pore complex protein Nup53, nucleoporin Nup35, 35 kD nucleoporin, mitotic phosphoprotein 44, MP-44, NUP35, MP44, NUP53)

Function

• component of the nuclear pore complex
• role in the association of MAD1 with nuclear pore complex
• interacts with TMEM48/NDC1, lamin B, NUP93, NUP155, NUP205

Structure

• belongs to the Nup53 family
• contains 1 MPPN domain (mitotic phosphoprotein N' end)

Compartment

• nuclear pore complex
• tightly associated with nuclear membrane & lamina

More general terms

• nucleoporin (nuclear pore complex protein)
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/608140
• UniProt: http://www.uniprot.org/uniprot/Q8NFH5.html