TOM1-like 1 protein (target of myb-like 1 protein, Src-activating & signaling molecule protein, TOM1L1, SRCASM)

Function

• adapter protein involved in signaling pathways (putative)
• phosphorylated on tyrosines by FYN
• phosphorylated TOM1L1 interacts with the SH2 & SH3 domains of signaling proteins, FYN, GRB2, PIK3R1
• promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions
• phosphorylated TOM1L1 interacts with FYN, GRB2, PIK3R1 Golgi, endosome

More general terms

• phosphoprotein

Additional terms

• target of Myb protein 1 (TOM1)

Database

• OMIM: https://mirror.omim.org/entry/604701
• UniProt: http://www.uniprot.org/uniprot/O75674.html