Golgi phosphoprotein 2; Golgi membrane protein GP73 (GOLPH2, GOLM1)

Function

• cellular response protein to viral infection
• cycles via cell surface & endosomes upon lumenal pH disruption
• glycosylated

Compartment

Golgi

Alternative initiation

• named isoforms=2

Expression

• widely expressed
• highly expressed in colon, prostate, trachea, stomach
• expressed at lower level in testis, muscle, lymphoid tissues, white blood cells, spleen
• predominantly expressed by cells of the epithelial lineage
• expressed at low level in normal liver

Pathology

• up-regulated in response to viral infection
  • induced by the E1A adenoviral protein

More general terms

• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/606804
• UniProt: http://www.uniprot.org/uniprot/Q8NBJ4.html