band 4.1-like protein 5 (EPB41L5, KIAA1548)

Function

• may contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells
• interacts with MPP5, CRB2 & CRB3

Structure

• the FERM domain binds to CRB1
• contains 1 FERM domain

Compartment

cytoplasm. cell junction, adherens junction

Alternative splicing

named isoforms=4

Notes

• associated with the plasma membrane
  • colocalizes with CTNNB1, an adherens junction marker (putative)

More general terms

• band 4.1-like protein (EPB41L)
• phosphoprotein

Additional terms

• protein 4.1; Band 4.1; P4.1; EPB4.1; 4.1R (EPB41 E41P)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57669
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:57669
• OMIM: https://mirror.omim.org/entry/611730
• UniProt: http://www.uniprot.org/uniprot/Q9HCM4.html