MADS box transcription enhancer factor 2D; myocyte enhancer factor 2D (MEF2D)

Function

• transcription factor
• binds specifically to the MEF2 element present in regulatory regions of many muscle-specific genes
• activates transcription via MEF2 element
• involved in muscle-specific &/or growth factor-related transcription
• interacts with HDAC4

Structure

heterodimer

Compartment

nucleus

Alternative splicing

named isoforms=6

Expression

• expressed in muscle cell lineages
• expressed in myotubes & undifferentiated myoblasts

More general terms

• MADS box transcription enhancer factor 2
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/600663
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4209
• UniProt: http://www.uniprot.org/uniprot/Q14814.html