chromodomain-helicase-DNA-binding protein 6; CHD-6; ATP-dependent helicase CHD6; Radiation-induced gene B protein (CHD6, KIAA1335, RIGB)

Function

• probable transcription regulator
• phosphorylated upon DNA damage, probably by ATM or ATR

ATP + H2O = ADP + phosphate

Structure

• belongs to the SNF2/RAD54 helicase family
• contains 2 chromo domains
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Compartment

nucleus (probable)

Alternative splicing

named isoforms=3

Expression

ubiquitous

More general terms

• chromodomain-helicase-DNA-binding protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=84181
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:84181
• UniProt: http://www.uniprot.org/uniprot/Q8TD26.html